Can Genetic Biomarkers Really Help Diagnose ADHD?

With the rise of precision medicine, researchers are exploring whether genetic biomarkers could support ADHD diagnosis. While promising, current evidence shows that genetics alone cannot provide definitive answers. 

Candidate Genes and Dopamine Regulation 
Genes such as DAT1, DRD4 and COMT are frequently studied in ADHD research. These genes regulate dopamine transport and breakdown, processes essential for attention and self-control. 

Heritability Without Certainty 
ADHD has a heritability estimate of around 70 to 80 per cent, indicating a strong genetic influence. However, ADHD is polygenic, meaning many genes contribute to small effects rather than one determining outcome. 

Limits of Genetic Testing 
Because there is no single genetic signature, genetic testing cannot currently diagnose ADHD. Future research may allow genetic profiles to support risk assessment or treatment personalisation. 

Assessment services informed by emerging genetic research often begin with an in-person adhd assessment. 

To support a broader neurodevelopmental understanding, you could also access your free Autism test now. 

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